Close editorial portrait of a woman resting her chin on her hands

Neurotoxins

Neurotoxins are a minimally invasive treatment that softens fine lines and wrinkles by temporarily relaxing the facial muscles behind them. Botox®, Dysport®, DAXXIFY® and Jeuveau® are the ones used in cosmetic treatment. Our aesthetic nurse injectors place them at Mafi Plastic Surgery in Fresno, California, tailored to your own facial features.

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What are
Neurotoxins?

Neurotoxins are popular, minimally invasive treatments that help soften the appearance of fine lines and wrinkles. They work by temporarily blocking the nerve signals that tell certain facial muscles to contract. When these muscles relax, the skin above them becomes smoother, helping soften wrinkles and create a more refreshed, natural-looking appearance. At Mafi Plastic Surgery, we offer Botox®, Dysport®, DAXXIFY®, and Jeuveau®.

Common treatment areas include the forehead, frown lines between the eyebrows, and crow’s feet around the eyes, but they can also be used in other areas of the face to create subtle changes, such as gently lifting the brows, softening a gummy smile, reducing a downturned mouth, or defining the jawline. Your aesthetic nurse injector will determine where treatment can best complement your natural features and goals.

Results are temporary and may last three to six months or longer, depending on the individual, the area treated, and the brand of neurotoxin used. Regular treatments can help maintain your results over time. Appointments are quick, usually taking less than 30 minutes, with little to no downtime, making neurotoxin treatments easy to fit into your schedule.

At Mafi Plastic Surgery, our aesthetic nurse injectors focus on creating natural-looking results that enhance your individual facial features and goals.

Neurotoxin treatments are quick, typically taking less than 30 minutes, with little to no downtime afterward.

Results are temporary and typically last three to six months or longer, depending on the individual, treatment area, and neurotoxin used. Regular treatments can help maintain your results over time.

The most common treatment areas are the forehead, frown lines between the eyebrows, and crow’s feet around the eyes. Neurotoxins can also be used in other areas of the face for subtle enhancements based on your individual features and goals.

These are the neurotoxins we trust and offer at Mafi Plastic Surgery. Your aesthetic nurse injector will recommend the best option and treatment areas based on your individual features and goals.

Vials of Botox® Cosmetic, Dysport®, DAXXIFY® and Jeuveau® grouped together against a white background
Under 30 MinutesMinimal Downtime3 to 6 MonthsForehead & Frown LinesCrow’s FeetBotox®, Dysport®, DAXXIFY®, Jeuveau®Natural ResultsAesthetic Nurse Injectors

Am I a candidate for neurotoxins?

Relax the muscle underneath, and the line above it softens.

Neurotoxins work by relaxing the muscles that create expression lines, helping soften the wrinkles that appear when you smile, frown, or squint. They may be a good option if you’re looking to soften:

Forehead Lines

Lines across the forehead caused by years of facial expressions.

Frown Lines

Lines between the eyebrows that become more noticeable when you frown or squint.

Crow’s Feet

Fine lines around the outer corners of the eyes that appear with smiling and squinting.

Other Expression Lines

Wrinkles caused by repeated facial movements rather than lost volume.

Minimal Downtime

A quick treatment, typically taking less than 30 minutes, with little to no downtime afterward.

Ongoing Maintenance

You understand that results are temporary and may require regular treatments to maintain your results.

Before: a neurotoxin patient of the practice’s aesthetic nurse injectors
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BeforeAfter
Neurotoxins

Movement softened,expression kept.

Each case below is one patient of the practice, photographed before treatment and after it settled. Drag the seam to compare. Neurotoxins relax the muscles that fold the skin, so the change shows most in the lines expression creates.

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Individual results vary. These are patients of our aesthetic nurse injectors, photographed at Mafi Plastic Surgery, and published with their permission. They are not a guarantee of your own outcome.

Common questions about neurotoxins

The cost of treatment depends on the neurotoxin used and how much is needed to achieve your desired results. After your consultation, your aesthetic nurse injector will discuss your treatment plan and provide your personalized pricing. Mafi Plastic Surgery offers financing through CareCredit, Cherry, and PatientFi, allowing eligible patients to spread the cost over monthly payments. Our team is happy to help you learn more about your financing options.

Still curious?Ask us directly →

Soften What
Expression Left

Sit down with one of our aesthetic nurse injectors in Fresno to find out whether a neurotoxin is the right answer for the lines you are seeing.

Prefer to talk? Call (559) 890-6500.

Medically reviewed by Parham Mafi, M.D., F.A.C.S., board-certified plastic surgeon at Mafi Plastic Surgery. This page is for education and is not a substitute for a personalized medical consultation.

Last medically reviewed August 2026Updated