
Dr. Zein Obagi’s line, built on high concentrations of retinol, antioxidants and peptides, in multi-step protocols that cleanse, exfoliate and protect.
ZO Skin Health
Medical-grade skin care is formulated with higher concentrations of active ingredients, clinically tested, and made to reach deeper than what you buy over the counter. Mafi Plastic Surgery carries two lines, ZO Skin Health and Alastin Skincare, and our med spa team in Fresno, California selects from them to build a routine around your skin.
Book a consultationMedical-grade means higher concentrations of active ingredients, clinically tested, formulated to work deeper than anything sold over the counter, and dispensed through a licensed professional rather than off a shelf. ZO Skin Health and Alastin Skincare are built on different science, and which of them you use is a decision we make with you.
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These lines are dispensed through licensed professionals, which is the point: nothing is picked off a shelf. Our esthetician, our licensed esthetician and our aesthetic nurse injectors look at your skin, hear what has actually been bothering you, and ask what you are using now.
ZO Skin Health works in multi-step protocols that cleanse, exfoliate and protect, built on high concentrations of retinol, antioxidants and peptides. Alastin uses TriHex Technology to clear away damaged proteins so the skin can rebuild its own collagen and elastin. The team selects from both against your concern, whether that is aging, acne, sun damage, inflammation or uneven tone.
Alastin is formulated for pre- and post-procedure care, supporting the skin as it heals and enhancing the result of treatments like microneedling and chemical peels. If you have something on the calendar, say so at the consultation. What you use before and after is part of the plan rather than an afterthought.
Skin moves with the season, with age, and with whatever else you have had done, so a regimen set once is a regimen that stops fitting. Come back and it gets revised: something added, something eased off, something you no longer need. Both lines are stocked at the practice in Fresno, so a refill is a stop by the office.
There is no single number, because what you leave with depends on your skin and on how many steps your routine actually needs. The team prices the plan before you commit to it. Mafi Plastic Surgery works with CareCredit, Cherry and PatientFi, and CareCredit in particular can be used again and again for skin care as well as for treatments, so a full regimen does not have to be one payment.
There is no single number, because what you leave with depends on your skin and on how many steps your routine actually needs. The team prices the plan before you commit to it. Mafi Plastic Surgery works with CareCredit, Cherry and PatientFi, and CareCredit in particular can be used again and again for skin care as well as for treatments, so a full regimen does not have to be one payment.
Sit down with our med spa team in Fresno to find out which products belong in your routine, and which ones do not.
Prefer to talk? Call (559) 890-6500.
Medically reviewed by Parham Mafi, M.D., F.A.C.S., board-certified plastic surgeon at Mafi Plastic Surgery. This page is for education and is not a substitute for a personalized medical consultation.
Last medically reviewed August 2026Updated